Assuming you're starting from the center of Downtown Houston and heading to 4026 Falls St in northeast Houston (ZIP 77026), the fastest route is typically: Get onto I-69/US-59 North from downtown. Take the exit for Collingsworth St / Cavalcade St. Turn right onto Collingsworth St. Turn left onto Russell St. Turn right onto Falls St. Continue to 4026 Falls St, Houston, TX 77026.